Bitola participates in town twinning to foster good international relations. Its current partners include:
- Pushkin, Russia
- Épinal, France
- Rijeka, Croatia
- Bursa, Turkey
- Kranj, Slovenia
- Rockdale, NSW, Australia
- Kremenchuk, Ukraine
- Pleven, Bulgaria
- Zemun, Serbia
- Kaiserslautern, Germany
- Prizren, Kosovo
- Korçë, Albania